Can inhalation allergies be cured?

Itchy eyes, a stuffy nose, and breathing difficulties—many people suffer from inhalation allergies such as hay fever or dust mite allergies. Hay fever, also known as allergic rhinitis, affects up to 160 million children and up to 120 million adults worldwide, depending on the region (Alnahas et al., 2023). But is there a way to permanently eliminate the allergy, or can only the symptoms be treated?

In this article, you will learn what causes inhalation allergies, which treatment options are available, and whether a cure is possible—or if affected individuals must manage the allergy throughout their lives.


Table of Contents


What is an inhalation allergy?

An inhalation allergy is an overreaction of the immune system to airborne allergens such as pollen, dust mites, or pet dander. The body mistakenly classifies these normally harmless substances as threats and releases histamine (a chemical messenger involved in allergic reactions), which causes typical symptoms such as sneezing, itching, or shortness of breath.

A common example is pollen allergy (hay fever), where affected individuals react seasonally to airborne pollen, experiencing symptoms such as a runny or congested nose and itchy eyes (Cleveland Clinic, 2022).

Causes and triggers of inhalation allergies

The underlying cause is a hypersensitive immune response, often influenced by genetic predisposition or environmental factors.

Category Examples
Pollen Grass, tree, and weed pollen (e.g., birch, ragweed)
Dust mites Mite feces in mattresses, carpets, and upholstery
Pet dander Skin flakes and saliva from cats, dogs, horses
Mold spores Damp environments, poorly ventilated spaces
Occupational allergens Flour dust (bakers), wood dust (carpenters), chemicals

Source: Cleveland Clinic, 2024

Common causes of allergy development:

Genetic predisposition – Allergies often run in families.
Air pollution & environmental factors – Fine dust and pollutants can sensitize the immune system.
Excessive allergen exposure – Frequent contact with potential allergens (e.g., pets, certain occupations) increases the likelihood of developing an allergy.

Source: Mayo Clinic, 2024

Can an inhalation allergy be cured?

A complete cure for inhalation allergies is rare. In most cases, the allergy remains a lifelong condition, but there are ways to reduce symptoms or even suppress them significantly.

The only therapy that can lead to long-term improvement or potentially a cure is specific immunotherapy (desensitization). This treatment gradually trains the immune system to tolerate the allergen, reducing allergic reactions or, in some cases, eliminating them completely.

The therapy is conducted under medical supervision, either through regular injections under the skin (subcutaneous immunotherapy, SCIT) or through drops or tablets placed under the tongue (sublingual immunotherapy, SLIT). Allergen-specific immunotherapy (AIT) has shown promising results for respiratory allergies such as allergic rhinitis and allergic asthma (Bernardini et al., 2024; Pfaar et al., 2022).

However, this therapy does not work for everyone and does not always lead to a complete cure. Still, symptom reduction of 50 to 80 percent is possible, significantly improving quality of life (UMC Utrecht, 2025).

Why is a cure for inhalation allergies rare?

A complete cure for inhalation allergies is uncommon because the immune system often retains the allergic response for life. The key reasons for this include:

  • Deeply ingrained immune system malfunction: Harmless substances like pollen or dust mites are mistakenly identified as harmful, and reversing this reaction is difficult.
  • Genetic predisposition: Many people have a hereditary tendency toward allergies, making the immune system permanently hypersensitive.
  • Constant allergen exposure: Pollen, dust, and other allergens are everywhere, making long-term suppression of the reaction challenging.
  • Variable effectiveness of immunotherapy: Desensitization can reduce symptoms, but it does not provide lasting results for all patients.
  • No complete immune adaptation: Unlike infections, the immune system does not naturally adjust or "heal" from allergies.

Source: Cleveland Clinic, 2022

Treatment options for inhalation allergies

For many people, the best strategy is to control symptoms by avoiding allergens or using medication. These measures help relieve discomfort but do not address the underlying cause of the allergy (AAFA, 2024). In addition to specific immunotherapy, two key approaches are particularly important: allergen avoidance and medication-based treatment.

1. Allergen avoidance – reducing exposure to triggers

The simplest way to relieve allergy symptoms is to avoid allergens whenever possible. However, complete avoidance is not always feasible. Here are some practical tips for allergen avoidance:

For pollen allergies: Keep windows closed during pollen season, use pollen screens, and change clothes after spending time outdoors.
For dust mite allergies: Use hypoallergenic bedding, clean mattresses regularly, and reduce indoor humidity.
For pet allergies: Avoid direct contact with animals, ventilate rooms frequently, and clean surfaces regularly.

2. Medication-based treatment – relieving symptoms

If allergen avoidance is not enough, medications can help manage allergic reactions.

Medication Effect Application Form
Antihistamines Block histamine effects, reduce itching and sneezing. Tablets, nasal sprays, eye drops
Corticosteroids Anti-inflammatory, reduces swelling and irritation. Nasal sprays, inhalers
Mast cell stabilizers Prevent histamine release, act as a preventive measure. Nasal sprays, eye drops
Leukotriene receptor antagonists Block allergic inflammatory responses. Tablets

Source: Drechsel, 2022

Early detection of inhalation allergies – home testing

If you suffer from persistent symptoms such as sneezing, itchy eyes, or breathing difficulties, you may wonder whether an allergy is the cause. An inhalation allergy test can help identify specific substances triggering your immune response.

With the Homed-IQ Inhalation Allergy Test, you can conveniently test from home whether you are sensitive to pollen, dust mites, pet dander, or other common allergens. The test analyzes your blood for specific IgE antibodies, which indicate allergic sensitization. After analysis in a certified laboratory, you will receive a detailed report on your individual allergy triggers.

Summary

A complete cure for inhalation allergies is rare, as the immune system typically retains the allergic response throughout life. Specific immunotherapy (desensitization) can provide long-term symptom relief but does not always lead to a full cure. In addition to this therapy, allergen avoidance and medication-based treatments are key measures for symptom management. Through targeted therapies and lifestyle adjustments, affected individuals can effectively control their symptoms and significantly improve their quality of life.

Allergens and Allergic Asthma. (n.d.). Asthma and Allergy Foundation of America | AAFA. Retrieved March 12, 2025, from https://aafa.org/asthma/asthma-triggers-causes/allergic-asthma/

Allergic Asthma: Causes, Symptoms, Tests & Treatment. (n.d.). Cleveland Clinic. Retrieved March 12, 2025, from https://my.clevelandclinic.org/health/diseases/21461-allergic-asthma

Allergies – Symptoms and causes. (2024, August 24). Mayo Clinic. Retrieved March 12, 2025, from https://www.mayoclinic.org/diseases-conditions/allergies/symptoms-causes/syc-20351497

Allergies: Symptoms, Reaction, Treatment & Management. (n.d.). Cleveland Clinic. Retrieved March 12, 2025, from https://my.clevelandclinic.org/health/diseases/8610-allergies

Leitlinie zur Allergen-Immuntherapie bei IgE-vermittelten allergischen Erkrankungen. (n.d.). AWMF Leitlinien. Retrieved March 12, 2025, from https://register.awmf.org/assets/guidelines/061-004l_S2k_Allergen-Immuntherapie-bei-IgE-vermittelten-allergischen_Erkrankungen_2022-10.pdf

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