Latex allergy: symptoms, risks and how to avoid reactions

Latex, a natural material used in a wide variety of products, can trigger allergic reactions in some people. If you have ever touched a balloon, worn medical gloves, or used a condom, you have likely come into contact with latex. But what happens when the body reacts negatively to it? Read on to learn everything about latex allergy.


Table of Contents


What is latex?

Latex is a natural, milky sap primarily obtained from the rubber tree (Hevea brasiliensis). This sap consists of water, sugar, and proteins and serves the tree as a defense against pests. Through various industrial processes, this sap is transformed into an elastic substance we know as rubber or latex. Due to its unique properties – elasticity, flexibility, and water resistance – latex is a highly sought-after raw material in many industries, from medicine to household products (Britannica, 2023).

Which products contain latex?

A wide range of products contains latex, including:

  • Medical gloves
  • Balloons
  • Condoms
  • Bandages
  • Pacifiers
  • Rubber bands
  • Shoe insoles

Source: Nguyen & Kohli, 2022

What is a latex allergy?

A latex allergy occurs when the body’s immune system is hypersensitive to certain proteins found in natural latex. There are different types of reactions to latex products:

  • Immediate reaction (Type I): This is a true allergic reaction in which the immune system produces specific antibodies called immunoglobulin E (IgE) against latex proteins. It occurs within minutes of contact with latex. With repeated exposure, certain cells release various chemicals, including histamine, which triggers typical allergy symptoms.

  • Allergic contact dermatitis (Type IV): This is a delayed reaction that usually occurs 48–72 hours after contact with the allergen (latex protein). It often presents as eczematous rashes at the site of contact. This type of allergy is less dangerous than Type I but can still be very uncomfortable and lead to skin problems.

Source: Nucera et al., 2020; NHS, 2023

For those affected, a latex allergy can significantly impact daily life. It requires constant vigilance to avoid contact with potential latex sources, especially in hospitals, dental practices, or when using everyday products that may contain latex. If left untreated, allergic reactions to latex can lead to serious health complications.

What are the risk factors for a latex allergy?

Anyone can develop a latex allergy, but some individuals are at greater risk. Risk factors for a latex allergy include:

  • Frequent contact with latex: When someone regularly comes into contact with latex, the body may begin to overreact and develop an allergic response. People who frequently wear latex gloves, such as medical personnel, dentists, or beauticians, are at increased risk.
  • Many surgical procedures: Both children and adults who have undergone multiple surgeries are at higher risk of developing a latex allergy due to repeated exposure to latex-containing medical products such as catheters or gloves.
  • Presence of other allergies: People with other allergies, such as allergic rhinitis, often also have a latex allergy. There is also a link between latex allergies and food allergies.

Source: Cleveland Clinic, 2020

Are there cross-allergies with latex allergy?

Many people with a natural latex allergy also show sensitivity to certain fruits. This phenomenon has been termed the “latex-fruit syndrome” after it was observed that a surprisingly high number of individuals allergic to latex also reacted to certain fruits. Around 40% of people with a latex allergy have latex-fruit syndrome, which is caused by cross-reactivity with food allergies. These cross-reactions can occur particularly with:

  • Bananas
  • Kiwi
  • Avocado
  • Chestnuts

The cause of this cross-reaction lies in the fact that these foods contain proteins similar to those found in latex. In addition to these fruits, cross-reactivity has also been described with other foods such as cassava, curry spice, potatoes, tomatoes, and bell peppers (Parisi et al., 2021).

What are the symptoms of a latex allergy?

Symptoms of a latex allergy can vary depending on the severity:

Mild reactions:

  • Itching or redness at the contact site
  • Sneezing or runny nose
  • Eye irritation

Moderate reactions:

  • Rash or urticaria (hives) over larger areas of the body
  • Coughing, wheezing, or difficulty breathing
  • Itchy, red, or watery eyes

Severe reactions (anaphylaxis):

  • Shortness of breath or wheezing
  • Swelling of the face, mouth, or throat
  • Rapid heartbeat
  • Confusion or dizziness
  • Nausea or vomiting
  • Loss of consciousness

At signs of a severe allergic reaction, emergency services should be contacted immediately (Mayo Clinic, 2022).

How is a latex allergy diagnosed?

A latex allergy is identified and confirmed through various diagnostic methods:

  • Medical history (anamnesis): The first step involves the doctor asking about symptoms that occur after contact with latex products. The medical history is also discussed to rule out other possible causes of the symptoms.
  • Skin test (prick test): In this test, a small drop of latex extract is applied to the skin and the area is then pricked with a needle. If the skin becomes red and swollen at the site, this may indicate an allergy.
  • Blood test: This test looks for specific antibodies to latex in the blood. A positive result suggests sensitization to latex.
  • Provocation test: In this test, the person is exposed to latex under controlled conditions to see if a reaction occurs. This test is only conducted if other tests are inconclusive and should always be carried out under medical supervision (Nguyen & Kohli, 2022).

It is important to note that if a latex allergy is suspected, a specialist—usually an allergist—should always be consulted. They can make an accurate diagnosis and provide appropriate recommendations for avoidance and treatment.

Have you noticed symptoms like itching, skin redness, swelling, or difficulty breathing after contact with latex-containing products?
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What can be done about a latex allergy?

General guidelines

  • Avoid contact with latex-containing products. This means identifying products that contain latex and using alternative options.
  • Inform medical personnel and dentists about your latex allergy before any procedures or treatments.
  • Wear a medical alert bracelet or carry a card that states your allergy.

Source: Mayo Clinic, 2022

Seek alternatives

  • For contraception, latex-free condoms made from polyurethane or other materials are available. These offer comparable protection against sexually transmitted diseases such as HIV, herpes, gonorrhea, chlamydia, and syphilis. It is essential to be informed about alternatives, as condoms play a key role in protecting against sexually transmitted infections.
  • Inform your partner about your allergy and discuss suitable alternatives for safe sex.
  • Always check the ingredients of lubricants and other intimate products for latex components.

Source: Cleveland Clinic, 2020

Emergency kit in case of a reaction

  • An emergency kit for individuals with a known latex allergy should contain specific medications, including epinephrine (adrenaline), which can be administered via an auto-injector (e.g., EpiPen) during severe allergic reactions to counteract life-threatening symptoms.
  • Antihistamines can help treat milder allergy symptoms, while corticosteroids can reduce the body’s inflammatory response.

It is essential to regularly check the expiration dates of medications and receive proper training from a doctor on how to use the auto-injector correctly. In addition, family members and close friends should also be familiar with the correct usage and the steps to take in an emergency (NHS, 2023).

Summary

Although not extremely common, latex allergies can pose serious health complications for those affected. It is important to recognize the symptoms, be aware of the risk of cross-reactions, and take measures to avoid triggers. With the right knowledge and precautions, people with latex allergies can live normal and healthy lives.

4 Non-Latex Condoms to Avoid Latex Allergies – Cleveland Clinic. (2020, October 15). Cleveland Clinic Health Essentials. Retrieved August 8, 2023, from https://health.clevelandclinic.org/have-a-latex-allergy-4-safe-condom-types-for-you/

Latex Allergy: Current Status and Future Perspectives. (2020, September 28). NCBI. Retrieved August 8, 2023, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532063/

Latex allergy – information for patients | CUH. (n.d.). Cambridge University Hospitals. Retrieved August 8, 2023, from https://www.cuh.nhs.uk/patient-information/information-for-patients-with-latex-allergy/

Latex Allergy – StatPearls. (2022, July 11). NCBI. Retrieved August 8, 2023, from https://www.ncbi.nlm.nih.gov/books/NBK545164/

Latex allergy – Symptoms and causes. (2022, October 21). Mayo Clinic. Retrieved August 8, 2023, from https://www.mayoclinic.org/diseases-conditions/latex-allergy/symptoms-causes/syc-20374287

Latex Allergy: What It Is, Symptoms, Prevention. (2020, October 26). Cleveland Clinic. Retrieved August 8, 2023, from https://my.clevelandclinic.org/health/diseases/8623-latex-allergy

Latex | Definition, Types, & Facts. (n.d.). Britannica. Retrieved August 8, 2023, from https://www.britannica.com/science/latex-chemical-compound

Parisi, C. A.S., & et al. (2021). Update on latex allergy: New insights into an old problem. World Allergy Organization Journal14(8). https://www.sciencedirect.com/science/article/pii/S1939455121000636

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